Galen Durant Reed1,2, Peder E. Larson1, John Kurhanewicz1,2, Daniel B. Vigneron1,2
1Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA, United States; 2Joint Graduate Group in Bioengineering, UCB / UCSF, Berkeley, CA, United States
The long acquisition times for the 3D phase encoding traditionally employed in proton magnetic resonance spectroscopic imaging (MRSI) of the prostate can be prohibitively long. A 3T MRSI sequence with a flyback echo-planar readout recently developed and clinically implemented at UCSF shows greatly reduced scan times. This time reduction allows for larger acquisition matrices and longer repetition times to avoid metabolite saturation. Comparison with a 1.5T 3D phase-encoded sequence showed that the flyback sequence can achieve comparable spatial resolution, improved spectral resolution, and significantly improved SNR in a shorter scan time.