Bndicte
Delattre1, Vincent Braunersreuther2, Jean-Nol
Hyacinthe1, Jean-Paul Valle1, Dimitri Van De Ville3,4
1University of Geneva - Faculty of
medicine, Geneva, Switzerland; 2Division of Cardiology -
Department of Medicine, Geneva University Hospital - Foundation for medical
researchers, Geneva, Switzerland; 3Department of Radiology and
Medical Informatics - University of Geneva, Geneva, Switzerland; 4Institute
of Bioengineering - Ecole Polytechnique Fdrale de Lausanne, Lausanne,
Switzerland
Small
animal cardiac imaging on clinical scanners allows contributing effectively
to translational medicine. However, hardware limitations prevent obtaining
the same space and time resolution than with dedicated instrumentation. Here,
we propose a novel method to improve time resolution for cardiac mouse
imaging. By combining two fast repetitions with temporal regularization based
on l1-minimization in the Fourier domain, we achieve a TR=6.5 ms with an
in-plane resolution of 257 μm2 and reduce efficiently
artifacts resulting from the combination of the two repetitions.