Yujin Jang1,
  Helen Hong1, Hak Jong Lee2, Sung Il Hwang2
1Division of Multimedia Engineering,
  Seoul Women's University, Seoul, Korea, Republic of; 2Department
  of Radiology, Seoul National University Hospital of Bundang, Seongnam-si,
  Korea, Republic of
To
  segment the prostate in MR images with a poor tissue contrast and shape
  variation, we propose a reliable and reproducible segmentation method using a
  prior knowledge of shape, geometry and gradient information. The prostate
  surface is generated by 3D active shape model using adaptive density profile
  and multiresolution technique. To prevent holes from occurring by the
  convergence of the surface shape on the local optima, the hole is eliminated
  by 3D shape correction using geometry information. In the apex of the
  prostate which has a large anatomical variation, the boundary is refined by
  2D contour correction using gradient information.
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