Dattesh D. Shanbhag1, Rakesh Mullick1,
Sumit K. Nath1, Catherine Oppenheim2, Marie Luby3,
Katherine D. Ku3, Lawrence L. Latour3, Steven Warach3,
- NINDS Natural History of Stroke Investigators3
1Imaging Technologies, GE Global
Research, Bangalore, Karnataka, India; 2Department of
Neuroradiology, Universit Paris-Descartes, Paris, France; 3NINDS,
NIH, Bethesda, MD, United States
In
context of acute ischemic stroke, we demonstrate that motion correction on
PWI data should be used only if motion is detected, rather than as a standard
pre-processing recipe in analysis pipeline. A motion detection scheme based
on image moments is shown to be effective in capturing motion during phase
volumes. Since the motion correction is the rate-limiting step in PWI data
analysis pipeline, moment based motion detection and selective motion
correction can result in significant time saving for processing PWI data.
Symmetry correction, a step commonly used for contralateral analysis,
produces lower estimates of perfusion lesion volumes if applied
retrospectively on quantitative maps rather than on bolus signal volumes.