Stefanie Remmele1, Tobias Voigt2, Jochen Keupp1, Christian Stehning1, Julien Sngas1
1Philips Research Europe, Hamburg, Germany; 2University of Karlsruhe, Karlsruhe, Germany
This work presents an approach to simultaneous and dynamic dR1, dR2* estimation that combines the beneficial features of currently used techniques for dynamic R1 quantification in DCE-MRI and for dynamic R2*-quantification in D(C)O2E-MRI. The technique aims at increasing the specificity of R2* BOLD imaging during respiratory challenges. Its accuracy and sensitivity is evaluated in phantom and breathold experiments.