Baris Turkbey1, Haresh Mani2, Vijay Shah3,4, Marcelino Bernardo3, 4, Ardeshir Rastinehad5, Thomas Pohida6, Yuxi Pang7, Dagane Daar3, Compton Benjamin5, Yolanda McKinney1, Joanna Shih8, Maria J. Merino2, Peter A. Pinto5, Peter L. Choyke1
1Molecular Imaging Program, NCI, NIH, Bethesda, MD, USA; 2Laboratory of Pathology, NCI, NIH, USA; 3Molecular Imaging Program, NCI, NIH, USA; 4Imaging Physics, SAIC Frederick, Inc., NCI-Frederick; 5Urologic Oncology Branch, NCI, NIH, USA; 6Division of Computational Bioscience, Center for Information Technology, NIH, USA; 7Philips Healthcare, USA; 8Biometric Research Branch, NCI, NIH, USA
Multiparametric MRI has better sensitivity for detecting larger (> 5 mm in diameter) and more aggressive (Gleason score of > 7) tumors. The use of the mold enables more exact correlation between each MR parameter and the histopathologic specimen. The customized mold provided tissues blocks that had a one to one correspondence with the in vivo MR.