Elizabeth Charles-Edwards1, Veronica Morgan1, Ayoma Attygalle2, Sharon Giles1, Thomas E. Ind3, Michael Davis4, John Shepherd3, Norman McWhinney5, Nandita deSouza1
1CRUK & EPSRC Cancer Imaging Centre, Institute of Cancer Research & Royal Marsden NHS Foundation Trust, Sutton, Surrey, United Kingdom; 2Histopathology, Royal Marsden NHS Foundation Trust, Sutton, Surrey, United Kingdom; 3Gynaecology, Royal Marsden NHS Foundation Trust, Sutton, Surrey, United Kingdom; 4Gynaecology, Kingston Hospital , Kingston, Surrey, United Kingdom; 5Gynaecology, Epsom & St. Helier NHS Trust, Epsom, Surrey, United Kingdom
Diffusion-weighted MRI using an endovaginal coil is a useful adjunct to T2-W imaging for detecting small tumours within the cervix. Following a cone biopsy/LLETZ procedure where distortion of normal tissue and granulation tissue is present, a tumor volume of 83 mm3 could be detected with 80% sensitivity, 94.7% specificity. A 5.3 mm maximal histological dimension was detected on MRI with 100% sensitivity, 100% specificity.