Heng Ma1, Lan Ge2, Jing An3, David Chen2, Lixin Jin4, Xiaoming Bi5, Renate Jerecic4, Kuncheng Li1, Debiao Li2,6
1Xuanwu Hospital, Capital Medical University, Beijing, China, People's Republic of; 2Northwestern University; 3Siemens Healthcare, MR Collaboration NE Asia, Siemens Mindit Magnetic Resonance; 4Siemens Healthcare, MR Collaboration NE Asia, Siemens Limited China; 5Siemens Healthcare, Cardiovascular MR R&D, USA; 6Cedars-Sinai Medical Center & UCLA
Myocardial perfusion MRI with SW-CG-HYPR allows increased spatial coverage (whole left ventricular coverage), resolution, signal-to-noise ratio and reduced motion artifacts. The accuracy of this technique for detecting CAD has not been determined in a large number of patients. In this work, we have prospectively examined the diagnostic value of adenosine-induced stress myocardial perfusion MRI using SW-CG-HYPR in 50 patients with suspected CAD. Using the SW-CG-HYPR method, perfusion MRI was able to cover the whole left ventricle with an accuracy of 90% and 93% based on per-patient and per-vessel analyses, respectively, using X-ray coronary angiography as a reference standard.