Abstract #0232

Is Iron the Source of Post Mortem Susceptibility Contrast in the Brain?

Ferdinand Schweser^1,2, Christian Langkammer^3,4, Andreas Deistung¹, Nikolaus Krebs⁴, Walter Goessler⁵, E. Scheurer⁴, K. Yen⁴, Franz Fazekas³, Jrgen R. Reichenbach¹, Stefan Ropele³

¹Medical Physics Group, Dept. of Diagnostic & Interventional Radiology 1, Jena University Hospital, Jena, Germany; ²School of Medicine, Friedrich Schiller University of Jena, Jena, Germany; ³Dept. of Neurology, Medical University of Graz, Graz, Austria; ⁴Ludwig Boltzmann Institute for Clinical-Forensic Imaging, Graz, Austria; ⁵Institute of Chemistry, Analytical Chemistry, University of Graz, Graz, Austria

Quantitative information of the regional non-heme tissue iron distribution bears clinical potential in the context of various neurological and psychiatric disorders. The goal of the current study was to investigate and compare the relation between tissue iron concentration and tissue magnetic susceptibility of in situ and fixed post mortem brain tissue.