Gregory R. Lee1,
Nicole Seiberlich1, Jeffrey L. Sunshine1,2, Timothy J.
Carroll3,4, Mark A. Griswold1,5
1Radiology, Case
Western Reserve University, Cleveland, OH, USA; 2Radiology,
University Hospitals Case Medical Center, Cleveland, OH, USA; 3Radiology,
Northwestern University, Chicago, IL, USA; 4Biomedical
Engineering, Northwestern University, Chicago, IL, USA; 5Biomedical
Engineering, Case Western Reserve University, Cleveland, OH, USA
3D Time-Resolved angiography remains challenging due to the high spatial and temporal resolutions required. In the present work, a multishot 3D radial VIPR acquisition with multi-echo readout and pseudorandom undersampling is combined with the recently developed GraDeS reconstruction algorithm. GraDeS allows the reconstruction of sparse images from highly undersampled data. A B0 fieldmap for correction of susceptibility artifact was derived from the same dataset. The resulting angiograms demonstrate clear arterial and venous separation. 1 mm^3 isotropic resolution is achieved at acceleration factors of 100-400 (1.1 s / 0.27s per frame) without the use of view sharing or a composite image.