Kevin Wen-Kai Tsai1, Aapo Nummenmaa2, Thomas Witzel2,3, Wei-Tang Chang4, Wei-Jui Kuo5, Fa-Hsuan Lin1,2
MR inverse imaging (InI) can achieve 100 ms temporal resolution with whole-brain coverage using highly parallel detection at the cost of compromised spatial resolution due to solving ill-posed inverse problems in image reconstruction. Here we propose the multi-projection InI (mInI) method. Using projection data in three orthogonal directions from all RF channels separately can achieve a high temporal resolution without compromising spatial resolution. Results of using mInI to study the hemodynamic responses in human visuomotor system from 12 participants using a 32-channel head coil array at 3T can achieve 100 ms temporal resolution and 4 mm3 isotropic spatial resolution.