Sanaz Mohajeri1,2, Tedros Bezabeh1, Scott B. King1, Omkar B. Ijare1, M. A. Thomas3, Gerald Minuk2, Jeremy Lipschitz2, Iain Kirkpatrick2, Ian C. P. Smith1
1National Research Council Institute for Biodiagnostics, Winnipeg, Manitoba, Canada; 2University of Manitoba, Winnipeg, Manitoba, Canada; 3University of California, Los Angeles, CA, United States
Magnetic Resonance Spectroscopy (MRS) is a method useful for the detection of mobile molecular species in a sample that have diagnostic utility. In vitro 1H MRS of human bile samples has been successful in detecting various hepatopancreatobiliary disorders. Therefore, there is a great interest in performing such analysis in vivo. We performed 1-D and 2-D 1H MRS of human gallbladder bile using a 3T clinical scanner and an optimized home-built receive array coil. Our preliminary efforts in obtaining good quality spectra are promising.