Daisuke Kokuryo1, Ichio Aoki1, Tsuneo Saga1
1Molecular Imaging Center,
National Institute of Radiological Sciences,
Ultra-short echo-time (UTE) imaging promises to be a powerful tool for lung parenchyma imaging. In this paper, signal changes in lung parenchyma and metastatic tumor induced by a positive contrast agent were evaluated using 3D UTE imaging for several flip angles. The signal intensity of UTE images in lung increased after Gd-DTPA administration. The enhancement was larger for FAs ≥ 10. The signal intensity of UTE images in tumor was also enhanced by Gd-DTPA. The results will be useful for optimizing chemotherapy with tumor targeting nanoparticles.