Mariska Petra Luttje1, Jannie Petra Wijnen1, Wybe J. M. van Der Kemp1, Peter R. Luijten1, Dennis W. J. Klomp1
The effects of susceptibility and breathing on the spectral resolution in the unilateral breast measurements of seven healthy female volunteers have been investigated. Using static 3rd order B0 shimming, a spectral resolution of 0.18 ppm can be obtained from the entire breast. This allows using 31P MRS at 7T to investigate phospholipid metabolism in the human breast in e.g. the assessment of cancer treatments. Furthermore, substantial dynamic B0 field alterations that strongly correlate to breathing are observed, that can be corrected for to improve spectral resolution and SNR even further.