Jacob U. Fluckiger1, Xia Li1, Jennifer Whisenant1, Lei Xu1, Junzhong Xu1, Todd E. Peterson1, John C. Gore1, Thomas Yankeelov1
1Institute of Imaging
Quantitative PET modeling is made difficult by the inability to separate tissue time activity curves into their constituent compartments. DCE-MRI modeling could be used in conjunction with dynamic PET imaging to overcome this limitation. The fractional volume parameters measured from a DCE-MRI scan can be used to separate tissue time activity curves and simplify PET modeling.