Ligong Wang1, Gregory Chang1, Jian Xu2, Renata L. R. Vieira1, Svetlana Krasnokutsky3, Steven Abramson3, Michael P. Recht1, Ravinder R. Regatte1
The purpose of this study was to assess T1rho values of cartilage and menisci in patients with osteoarthritis (OA) at 3T. Subjects with varying degrees of OA (K-L Score = 1-4, n = 30) were scanned. Statistically significant differences (P < 0.05) were identified between cartilage T1rho values of moderate-severe OA subjects in the lateral femoral anterior sub-compartment and doubtful-minimal OA subjects in the lateral and medial compartments. There were statistically significant differences in meniscus T1rho values of the medial posterior sub-region of subjects with moderate-severe OA and all sub-regions in the lateral and medial compartments of subjects with doubtful-minimal OA. Meniscus and cartilage T1rho values correlate with conventional MR findings of different degrees of degeneration.