Sahar Soleimanifard1, Khaled Z.
Abd-Elmoniem2, Emi Z. Murano1, M. R. Abraham1,
Theodore P. Abraham1, Jerry L. Prince1
1The Johns Hopkins
University, Baltimore, MD, United States; 2National Institute of
Diabetes & Digestive and Kidney Disease, Bethesda, MD, United States
Assessment of viability in myocardial disease continues to be of interest to clinicians. Principal strain patterns have been shown to change with ischemic injury, and can provide a sensitive index of viability. However, clinical use of principal orientations is extremely rare due to the existing noise in current measurements of angles. In this work, a reliable method of measuring principal strain angles was proposed. Consistency of the angles in the normal myocardium, combined with the results in the dysfunctional tissue in a porcine model, confirms the potential of principal strain orientations in assessment of viability.