Meeting Banner
Abstract #1424

Short Echo-Time MRSI of Human Brain at 7 Tesla with Improved Shimming & Fat-Suppression

Indrajit Saha1,2, Jay Moore1,3, Saikat Sengupta1,4, Subechhya Pradhan1,3, James M. Joers5,6, John C. Gore1,2

1Vanderbilt University Institute of Imaging Science, Vanderbilt University, Nashville, TN, United States; 2Department of Radiology & Radiological Sciences, Vanderbilt University, Nashville, TN, United States; 3Department of Physics & Astronomy, Vanderbilt University, Nashville, TN, United States; 4Department of Biomedical Engineering, Vanderbilt University, Nashville, TN, United States; 5Department of Radiology, Childrens Hospital of Wisconsin, Milwaukee, WI, United States; 6The Medical College of Wisconsin, Milwaukee, WI, United States


The acquisition of high quality MR spectroscopic imaging data at 7 T requires overcoming several problems associated with the physics of high field MRSI. We present our ongoing work on developing 2-D/single-slice MRSI methodology at 7 T human MR system by using image-based shimming, and B1-insensitive composite-pulses for improved skull-lipid suppression in a short echo-time STEAM sequence. This preliminary work shows the promises of improvements achievable at 7 T for exploitation of SENSE acceleration in MRSI acquisitions.