Shunichi Koda1, Jonathan Goodwin1, Valery Khramtsov2, Hirotada Fujii3, Hiroshi Hirata1
1Division of Bioengineering & Bioinformatics, Graduate School of Information Science & Technology, Hokkaido University, Sapporo, Hokkaido, Japan; 2Davis Heart & Lung Research Institute & The Division of Cardiovascular Medicine, The Ohio State University, Columbus, OH, United States; 3Center for Medical Education, Sapporo Medical University, Sapporo, Hokkaido, Japan
We demonstrated a newly developed method of pH mapping based on electron paramagnetic resonance (EPR). To reduce the missing-angle and the field-of-view of spectral-spatial images, EPR spectra at lower and center components of pH-sensitive nitroxyl radicals were individually measured. Reasonable pH values for test tubes were obtained with our pH mapping method. In this study, we obtained pH values with low standard deviation (}0.05 pH).