Matthew C. Murphy1, Kevin .J Glaser1, Bradley D. Bolster, Jr.2, Daniel V. Litwiller3, Scott A. Kruse1, Richard L. Ehman1
1Department of Radiology, Mayo Clinic, Rochester, MN, United States; 2MR R&D Collaborations, Siemens Healthcare, Rochester, MN, United States; 3Global Applied Science Laboratory, GE Healthcare, Rochester, MN, United States
MRE is a phase-contrast MRI technique for noninvasively measuring tissue stiffness. MRE of the brain is currently under investigation for its potential to aid in the diagnosis of brain diseases. A robust brain MRE exam should be reproducible even when performed on different MR platforms. The purpose of this work was to assess the reproducibility of MRE of the brain on two platforms manufactured by GE and Siemens. The results indicate that the two platforms yield significantly correlated stiffness measurements, and that the mean measurements on each platform do not differ from each other.