Ai-Ling Lin1, Peter Kochunov1,
Peter T. Fox1, Amy Ramage1, Hsiao-Ying Wey1,
Timothy Q. Duong1,
1Research Imaging Institute, University of Texas Health Science Center, San Antonio, TX, United States; 2Department of Psychiastry, University of Texas Health Science Center, San Antonio, TX, United States
The purpose of the study was to determine the relationship between the basal cerebral blood flow (CBF), cortical gray matter thickness (GMT) and white matter myelination in adolescents using MRI methods. Our results showed that gray matter pruning and white matter myelination occurred in parallel and the CBF reduction was mainly contributed by the reduced rate of myelination.