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Abstract #2010

Preparation of DiffusionWeighted MR Image Data for Cortical Parcellation

Zoltan Nagy1, David Lee Thomas2, Nikolaus Weiskopf1, Martin Sereno3,4

1Wellcome Trust Centre for Neuroimaging, University College London, London, United Kingdom; 2Institute of Neurology, Department of Brain Repair & Rehabilitation, University College London, London, United Kingdom; 3Department of Psychology, University College London, London, United Kingdom; 4Department of Psychology, Birkbeck College, London, United Kingdom


Both cognitive and anatomical neuroscience relies on commonly held reference systems such as the Brodmann map. Unfortunately, these maps are relatively coarse and ignore interindividual individual variability. Both these limitations can be overcome by MRI, although the exact contrast is unclear. We propose diffusionweighted images, present a image processing pipeline and demonstrate reproducible signal which is specific to the given cortical region the voxel resides in. Such data should allow computer intensive pattern recognition methods to parcellate the human cortex invivo.