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Abstract #2132

Can Hippocampal Size Predict Cognitive Impairment in Post-Stroke Patients?

Efrat Kliper1,2, Einor Ben Assayag3, Shani Shenhar-Tsarfaty2,3, Lodmila Shopin3, Hen Hallevi3, Eitan Uriel3, Amos Korczyn A3, Natan Meir Bornstein3, Talma Hendler1, Orna Aizenstein4, Dafna Ben Bashat D5

1The Wohl institute for Advanced Imaging, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel; 2Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel; 3Departments of Neurology, Tel Aviv Sourasky Medical Center, Israel, Israel; 4Departments of Radiology, Tel Aviv Sourasky Medical Center, Israel, Israel; 5The Wohl Institute for Advanced Imaging, Tel Aviv Sourasky Medical Center, Israel, Israel


Patients with ischemic stroke are at risk for developing cognitive impairment. Hippocampal size was calculated from 102 first-ever stroke patients using FreeSurfer. At baseline, patients with smaller hippocampi (below median) did not differ in their parameters (cognitive scores, NIHSS and years of education) from those with larger hippocampi. Six months after the event, improvements were observed in cognitive scores for both groups. However, 12 months post-stroke, patients with larger hippocampi presented better cognitive function compared to the other group. These preliminary results may suggest that stroke patients presenting with smaller hippocampi are prone to develop cognitive decline 12 months later.