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Abstract #2505

Longitudinal Regional Brain Development in Infants from Four to Nine Months of Age

Arvind Caprihan1, Mustafa S. Cetin1, Joy Van Meter2, Jean R. Lowe3, John P. Phillips2,4

1Mind Research Network, Albuquerque, NM, United States; 2Mind Research Network, Albuquerque, United States; 3Department of Pediatrics, University of New Mexico, Albuquerque, United States; 4Department of Neurology, University of New Mexico, Albuquerque, United States


We report normal developmental changes in regional brain tissue volumes in children from four to nine months of age. This is a longitudinal study where the growth of each child is individually studied. This data will be useful in mapping the trajectory of normal brain development during the childs first year, which is usually accompanied by rapid growth. The data allows us to study the normal trajectory of brain development. The average growth in brain volume was 20% with the gray matter having the fastest growth of 34%. In the paired analysis for the longitudinal analysis the gray matter had the fastest growth in the subgenual regions (69%), and the white matter had the fastest growth in the DLPF region (29%).