Tzu-Ching Shih1,2, Jeon-Hor Chen2,3, Muqing Lin4, Daniel Chang4, Ke Nie4, Orhan Nalcioglu4,5, Min-Ying Su4
1Department of Biomedical Imaging & Radiological Science, China Medical University, Taichung, 40402, Taiwan; 2Department of Radiology, China Medical University Hospital, Taichung, 40402, Taiwan; 3Tu & Yuen Center for Functional Onco-Imaging & Department of Radiological Sciences, University of California, Irvine, Irvine, CA 92697 , United States; 4Tu & Yuen Center for Functional Onco-Imaging & Department of Radiological Sciences, University of California, Irvine, Irvine, CA 92697, United States; 5Department of Cogno-Mechatronics Engineering, Pusan National University, Busan 609-735, Korea, Republic of
Usually, a breast tumor is harder than any tissue around it and the shape of benign masses is round or oval. By contrast, a malignant tumor is irregular in shape and has the invasive characteristics. Little is known about the influence of the morphology of fiborglandular tissues on breast density. Fibroglandular tissues would affect breast density. Breast compression changes breast density that indirectly influences the assessment of breast cancer risk. Thus, the purpose of this study is to investigate the effect of the morphology of fibroglandular tissue on the projected breast density after the breast compression based on a non-linear deformation using patient-specific magnetic resonance images.