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Abstract #3002

Test-Retest Reproducibility of Whole-Body Fat Water Imaging at 3 Tesla Compared to DEXA

Edward Brian Welch1,2, Malcolm J. Avison1,2, Kevin D. Niswender3, Johan Berglund4, Joel Kullberg4, Lars Johansson4, Morten Bruvold5, Heidi J. Silver3

1Vanderbilt University Institute of Imaging Science, Vanderbilt University, Nashville, TN, United States; 2Department of Radiology & Radiological Sciences, Vanderbilt University, Nashville, TN, United States; 3School of Medicine, Vanderbilt University, Nashville, TN, United States; 4Department of Radiology, Uppsala University, Uppsala, Sweden; 5MR Clinical Science, Philips Healthcare, Best, Netherlands


Whole-body MRI has great potential for quantifying the amount, type and distribution of adipose tissue to help better understand its metabolic consequences. Multi-gradient-echo MR acquisitions have been successfully used to quickly acquire whole-body fat-water imaging data sets. Dual energy x-ray absorptiometry (DEXA) is widely used in studies of body composition, but few direct comparisons of the performance of fat-water MR imaging (FWMRI) to DEXA are available, especially for 3T FWMRI. Here we present test-retest results of scanning 12 obese female subjects using a 3T mFFE whole-body FWMRI sequence as well as DEXA.