Yin Huang1, Ethan Brodsky1, Kevin Johnson1, Eric Bultman2, Debra Horng1,3, Sean Fain1,3, Scott Reeder1,3
1Medical Physics, University of Wisconsin Madison, Madison, WI, United States; 2Biomedical Engineering, University of Wisconsin Madison, Madison, WI, United States; 3Radiology, University of Wisconsin Madison, Madison, WI, United States
A novel method for acquiring dynamic contrast-enhanced (DCE) MRI of liver perfusion with full abdominal coverage is used to measure the blood supply to liver parenchyma and focal liver lesions non-invasively. This study aims to provide semi-quantitative metrics to evaluate 3D regional perfusion in a feasibility study to measure perfusion in focal liver lesions. The method is designed to predict long-term tumor response to chemotherapy by providing quantitative measures of early changes in perfusion specific to liver tumors.