Yongxian Qian1, Ashley A. Williams2, Constance R. Chu2, Fernando E. Boada1
1Radiology, University of Pittsburgh, Pittsburgh, PA, United States; 2Orthopaedic Surgery, University of Pittsburgh, Pittsburgh, PA, United States
When voxel size is decreased (or image resolution is increased), the impact of encoding gradient and B0-field inhomogeneity on T2* time is decreased and as a result, T2* time is supposed to be closer to T2 value. This work, however, shows that T2* in cartilage explants from human knees does not approach to T2 value when increasing image resolution. The reason for this might be that inhomogeneous microenvironment in tissue dominates local field and T2* values.