Xiaodong Zhong1, Bruce S. Spottiswoode2,
Craig H. Meyer3,4, Frederick H. Epstein3,4
1MR R&D Collaborations,
Siemens Healthcare, Atlanta, GA, United States; 2MRC/UCT Medical
Imaging Research Unit, University of Cape Town, Cape Town, Western Cape,
South Africa; 3Radiology Department, University of Virginia,
Charlottesville, VA, United States; 4Biomedical Engineering
Department, University of Virginia, Charlottesville, VA, United States
Two-dimensional (2D) cine DENSE provides a time series of pixel-wise displacement and strain measurements for the myocardium through the cardiac cycle. Previous cine DENSE studies used fast imaging techniques such as echo-planar (EPI) and spiral for rapid k-space data sampling. In this study, cine DENSE sequences were developed that employed three different k-space trajectories, namely conventional bottom-up interleaved EPI, flyback bottom-up interleaved EPI, and interleaved spiral. SNR efficiency and myocardial strain measured with these three techniques were compared. The three techniques produced similar strain results, although the SNR efficiency of spiral cine DENSE was higher than the other two.