Kakuya Kitagawa1, Hideki Miyagi1, Shingo Kato1, Yeonyee Elizabeth Yoon1, Motonori Nagata1, Shinichi Takase1, Andreas Sigfridsson2, Hajime Sakuma1
1Radiology, Mie University Hospital, Tsu, Mie, Japan; 2Center for Medical Image Science & Visualization, Linkping University, Linkping, Sweden
We assessed the hypothesis that myocardial strain measured by DENSE MRI can accurately diagnose the extent of LV myocardial injury in patients with AMI. Myocardial strains were quantified by DENSE MRI and custom made software in 20 patients with AMI treated with primary PCI, and were compared with LGE-MRI. Myocardial strains were significantly reduced in segments with transmural infarction compared with those without. The LV global strain showed a good correlation with LV infarct size. Myocardial strains by DENSE MRI showed high intra- and inter-observer reproduciblity. DENSE MRI may be highly useful for monitoring functional recovery of LV myocardium.