Hua Guo1,2, Ed X. Wu3,4, Wenchuan Wu1,2, Xiangyang Ma5, Guangzhi Wang1,2, Chun Yuan2,6
1Biomedical Engineering Department, Tsinghua University, Beijing, China, People's Republic of; 2Center for Biomedical Imaging Research, Tsinghua University, Beijing, China, People's Republic of; 3Laboratory of Biomedical Imaging & Signal Processing, the University of Hong Kong, Hong Kong, Hong Kong; 44Department of Electrical & Electronic Engineering, the University of Hong Kong, Hong Kong, Hong Kong; 5Philips Research Asia, Shanghai, China, People's Republic of; 6Department of Radiology, University of Washington, Seattle, WA, United States
Increased B0 and B1 inhomogeneity, together with increased motion artifacts, present challenges for cardiac imaging and quantification at 3T. Although breathhold acquisition method can improve the reproducibility of T2* and T2 measurement, the B1 nonuniformity may deteriorate their accuracy and confound the final diagnosis for monitor iron overload in patients with thalassaemia major. This study measured myocardial T2* and T2 in normal subjects at 3T with multi-transmit technology using single-breathhold acquisitions. The preliminary results demonstrated the effectiveness of the multi-transmit technique for myocardial T2* and T2 quantification improvement at 3T.