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Abstract #3419

In Vivo Short Spin-Echo 1H MR Spectroscopy with Macromolecule Suppression

Xi Chen1,2, Laura M. Rowland2, Yihong Yang1

1Neuroimaging Research Branch, Nation Institute on Drug Abuse, Baltimore, MD, United States; 2Maryland Psychiatric Research Center, University of Maryland School of Medicine, Baltimore, MD, United States


A broadband outer volume suppression scheme is proposed to compensate the potential subtraction error of the ISIS module in the SPECIAL sequence; an macromolecule suppression scheme is also proposed using a modified SPECIAL sequence. A similar SNR as the STEAM spectroscopy is achieved.