Martin G. Busch1,2, Jrgen Finsterbusch1,2
1Department of Systems
Neuroscience, University Medical Center
Conventional single-voxel localization based on cross-sectional RF excitations suffers from partial volume effects if the target volume is not cuboidal. 2D-selective RF (2DRF) excitations are able to define an arbitrary excitation profile within a plane and can be used to adapt the voxel shape to the target. This is demonstrated in vivo in the human brain for 2DRF excitations based on a PROPELLER trajectory which allow obtaining high-resolution profiles at echo times of 30 ms. Compared to a previous in vivo study, the SNR efficiency is considerable improved because the excitation k-space centre is covered with each shot.