John Graner1, Hai Pan1,
Ping-Hong Yeh1, Binquan Wang1, Terrence R. Oakes1,2,
Wei Liu1,2, Louis M. French3, Fletcher Munter2,
Gerard Riedy2,4
1TBI Image Analysis Lab,
Uniformed Services University of the Health Sciences / HJF, Bethesda, MD,
United States; 2National Capital Neuroimaging Consortium, Walter
Reed Army Medical Center, Washington, DC, United States; 3Defense
& Veterans Brain Injury Center, Walter Reed Army Medical Center,
Washington, DC, United States; 4National Intrepid Center of
Excellence, Bethesda, MD, United States
Fourteen (14) USA military TBI victims and 11 control subjects underwent fMRI while performing an N-back working memory task. Significant group differences were seen in the cerebellum in the 3-back vs. 1-back contrast. A preliminary investigation of heterogeneity within the group analysis results also suggests greater activation variability in the TBI population that may need to be accounted for when attempting traditional voxel-based group analysis.