John Graner1, Hai Pan1, Ping-Hong Yeh1, Binquan Wang1, Terrence R. Oakes1,2, Wei Liu1,2, Louis M. French3, Fletcher Munter2, Gerard Riedy2,4
1TBI Image Analysis Lab, Uniformed Services University of the Health Sciences / HJF, Bethesda, MD, United States; 2National Capital Neuroimaging Consortium, Walter Reed Army Medical Center, Washington, DC, United States; 3Defense & Veterans Brain Injury Center, Walter Reed Army Medical Center, Washington, DC, United States; 4National Intrepid Center of Excellence, Bethesda, MD, United States
Fourteen (14) USA military TBI victims and 11 control subjects underwent fMRI while performing an N-back working memory task. Significant group differences were seen in the cerebellum in the 3-back vs. 1-back contrast. A preliminary investigation of heterogeneity within the group analysis results also suggests greater activation variability in the TBI population that may need to be accounted for when attempting traditional voxel-based group analysis.