Zion Tsz Ho Tse1, Charles L. Dumoulin2, Gari Clifford3, Michael Jerosch-Herold1, Daniel Kacher1, Raymond Kwong4, William Gregory Stevenson4, Ehud Jeruham Schmidt1
1Radiology, Brigham & Women's Hospital, Boston, MA, United States; 2University of Cincinnati College of Medicine, Cincinnati, OH, United States; 3Department of Engineering Science, University of Oxford, Oxford, United Kingdom; 4Cardiology, Brigham & Women's Hospital, Boston, MA, United States
A real-time MRI-compatible 12-lead ECG monitoring system was developed, based on a modified digital ECG system connected to a strong processing platform, which performed a novel 3-D QRS-complex detection algorithm in <5ms, as well as adaptive filtering to remove Magneto-Hydro-Dynamic (MHD) voltages. The system was tested in 1.5T and 3T MRIs on 7 subjects (5 volunteers and 2 arrhythmia patients). Results showed high-fidelity MHD-free ECGs, with restoration of the true S-T segment signal for ischemia monitoring, and reliable QRS complex detection for scanner triggering. Non-invasive beat-to-beat stroke volume estimations were derived from time-integration of systolic MHD voltages.