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Abstract #3761

Preliminary Accuracy Evaluation of 3T MRI-Guided Transperineal Prostate Biopsy with Grid Template

Junichi Tokuda1, Kemal Tuncali1, Iulian Iordachita2, Sang-Eun Song1, Andriy Fedorov1, Sota Oguro1, Andras Lasso3, Fiona M. Fennessy1, Yi Tang1, Clare M. Tempany1, Nobuhiko Hata1

1Department of Radiology, Brigham & Women's Hospital, Boston, MA, United States; 2The Johns Hopkins University, Baltimore, MD, United States; 3School of Computing, Queen's University, Kingston, ON, Canada


This paper reports our initial feasibility study of MRI-guided core needle biopsy of the prostate in a 70cm bore 3-Tesla MRI scanner. Biopsy targets were defined on an intra-procedural T2 image as well as pre-operative MR images registered to the intra-procedural T2 image prior to the needle placement. The needle was guided by a specially-designed needle guidance grid template, which was registered to the image coordinate system by a z-shaped calibration frame. Our clinical study on 5 patients demonstrated that the procedure was feasible with needle placement accuracy of 4.9 mm.