David Saloner1,2, Daniel Hurwit1,2,
Vitaliy Rayz1,2, Loic Boussel3, Alastair Martin1,
William Young4, Wade Smith5, Nerissa Ko5,
Michael Lawton6
1Radiology & Biomedical
Imaging, University of California San Francisco, San Francisco, CA, United
States; 2Radiology, VA Medical Center San Francisco, San
Francisco, CA, United States; 3Radiology, Louis Pradel Hospital,
Lyon, France; 4Anesthesiology, University of California San
Francisco, San Francisco, CA, United States; 5Neurology,
University of California San Francisco, San Francisco, CA, United States; 6Neurosurgery,
University of California San Francisco, San Francisco, CA, United States
Patients with untreated intracranial aneurysms were imaged at serial intervals to monitor changes in those aneurysms over time. CE-MRA and balanced steady state imaging were performed to assess changes in lumen and intralumenal thrombus. In 36% of interval studies there were no changes; in 30% there was a reduction in lumenal volume secondary to thrombus deposition; and the remaining subjects showed lumenal growth both for aneurysms in the anterior and posterior circulation. 3D MRA/I methods are powerful tools for the non-invasive monitoring of evolution of vascular disease.