Joao M. N. Duarte1,2, Rolf Gruetter1,3
1Laboratory for Functional
& Metabolic Imaging, Center for Biomedical Imaging, Ecole Polytechnique,
Lausanne, Vaud, Switzerland; 2Faculty of Biology & Medicine,
University of Lausanne, Lausanne, Vaud, Switzerland; 3Department
of Radiology, Universities of Lausanne & Geneva, Switzerland
Glucose is the primary fuel required for brain function. We now evaluated brain glucose dynamics by employing a four-state conformational model that accounts for transport inhibition, and a dynamic method that allows distinguishing the parameters defining transport from comsumption.