Rajakumar Nagarajan1, Michael Albert Thomas1, Benjamin M. Ellingson1, Langston Holly2, Noriko Salamon1
Cervical spondylosis is a general term for age-related wear and tear affecting the joints in the neck. Proton (1H) magnetic resonance spectroscopy (MRS) has been widely used over the last few years to differentiate metabolic changes associated with neurological disease in the brain. This present study attempts to quantitate metabolites in cervical spine using point resolved spectroscopy (PRESS) on a 3T MRI scanner processed by the LC model software. Our preliminary results show significantly increased total choline, and increasing trend of lactate (Lac) and decreasing trend of N-acetylaspartate (NAA) in the spondylosis patient group.