Chang-Hoon Choi1,2, David J. Lurie1
1Aberdeen Biomedical Imaging Centre, University of Aberdeen, Aberdeen, Scotland, United Kingdom; 2MR Solutions Ltd., Guildford, Surrey, United Kingdom
Magnetisation transfer contrast (MTC) MRI is normally implemented at a fixed and high magnetic field (B0) but has only rarely been studied at a range of B0 due to the limitations of available MRI scanners. The use of fast field-cycling with an actively frequency switchable RF coil affords the ability to determine the MT effect over a range of magnetic fields, by rapidly switching B0 in concert with the coils resonance frequency. In this work, we used field-cycling to evaluate the MT effects of 1%, 2% and 4% agarose samples at the five different B0 levels by measuring MT ratios.