Thomas Christen1, Georges Hankov1, Heiko Schmiedeskamp1, Roland Bammer1, Greg Zaharchuk1
1Department of Radiology, Stanford University, Stanford, CA, United States
The objective of this study was to use the variations in R2 and R2* relaxation times induced by the inhalation of carbogen (95% O2, 5% CO2) to create parametric maps of the Vessel Size Index and Cerebral Blood Volume. The use of a gradient and spin echo EPI sequence allowed the acquisition of VSI and CBV values simultaneously with a high temporal resolution. This enabled the determination of a stable period during which the estimates are accurate. The measurements were performed in 5 healthy volunteers at 3.0T and the values obtained were in accord with past studies.