Noam Ben-Eliezer1, Eddy Solomon2, Elad Harel3, Nava Nevo4, Lucio Frydman2
1Center for Biomedical Imaging, New-York University, New-York, NY, United States; 2Chemical-Physics, Weizmann Institute of Science, Rehovot, Israel; 3Chemistry, Northwestern University, Evanston, IL, United States; 4Biological-Regulation, Weizmann Institute of Science, Rehovot, Israel
A new MR encoding approach has been recently introduced based on sequential encoding of the image spatial domain. An interesting aspect of this Spatiotemporal-Encoding (SPEN) technique, stems from its ability to carry out a progressive, voxel-by-voxel refocusing of all T2* dephasing throughout the data acquisition, allowing it to overcome sizable field inhomogeneities. This work demonstrated SPENs potential for imaging near metallic implants, using in-vivo mouse models. Cartesian and Back-Projected SPEN MRI were implemented on a 7T microimaging unit, and compared versus conventional Spin-Echo scheme analogues. In all cases, unambiguously superior images arise from the fully refocused spatiotemporally-encoded protocols.