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Abstract #0252

Diffusion Tractography in Term Neonates with Hypoxic-Ischemic Encephalopathy: Projection Fiber System & Corpus Callosum Involvement as Predictors of Neurodevelopmental Outcome

Katyucia de Macedo Rodrigues1, Maria de Carmen Fons Stupina2, 3, Ainsley MacLean4, Janet Soul2, Rudolph Pienaar5, Omar Khwaja2, P. Ellen Grant5

1Radiology, Children's Hospital Boston, Boston, Massachusettes, United States; 2Neurology, Children's Hospital Boston, Boston, Massachusettes, United States; 3Pediatric Neurology, Sant Joan de Seu Hospital for Children, Barcelona, Spain; 4Neuroradiology, Brigham and Women's Hospital, Boston, Massachusettes, United States; 5Center for Fetal-Neonatal Neuroimaging & Developmental Science, Children's Hospital Boston, Boston, Massachusettes, United States


We performed a tractography-based DTI analysis of projection and comissural tracts in term/near term neonates who presented perinatal HIE and had a brain MRI performed within 7 postnatal days and neonates with normal MRI without HIE and studied its correlation with early motor outcome.