Manojkumar Saranathan1, Dan Rettmann2, Brian A. Hargreaves1, Sharon Clarke1, Shreyas S. Vasanawala3
1Radiology, Stanford University, Stanford, CA , United States; 2Global Applied Science Laboratory, GE Healthcare, Rochester, MN, United States; 3Radiology, Stanford University, Stanford, CA, United States
High spatio-temporal resolution is essential in hepatobiliary imaging to characterize lesion morphology and to assess contrast uptake. In addition, late arterial phase imaging is critical for hypervascular tumors such as hepatocellular carcinoma (HCC) and neuroendocrine metastases. We demonstrate feasibility and clinical performance of a new high spatio-temporal resolution technique called DISCO (DIfferential Sub-sampling with Cartesian Ordering) that combines a dual-echo SPGR sequence with pseudo-random variable density k-space segmentation and a view sharing reconstruction. A high spatial resolution of 1.1x1.5x3 mm over 60 slices was routinely achieved with a temporal resolution of ~4 seconds, enabling clear delineation of angiographic, hepatic arterial, hepatic venous and portal venous phases.