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Abstract #0528

Clinical Evaluation of Peripheral Non-Contrast Enhanced MR Angiography (NCE-MRA) Using Steady-State Free Precession (SSFP) & Flow Sensitive Dephasing (FSD) in Diabetes

SUMMA25Na Zhang1, Zhaoyang Fan2, Fei Feng3, Pengcheng Liu4, Xin Liu1, Dehe Weng5, Renate Jerecic, Yongming Dai5, Hairong Zheng1, Debiao Li2

1Paul C. Lauterbur Research Centre for Biomedical Imaging, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong, China; 2Cedars Sinai Medical Center and University of California, Los Angeles, CA, United States; 3Department of Radiology, Peking University Shenzhen Hospital, Shenzhen, Guangdong, China; 43Department of Radiology, Peking University Shenzhen Hospital; 5Siemens Healthcare, Shanghai, China


A novel peripheral non-contrast enhanced MR Angiography (NCE-MRA) using SSFP and flow-sensitive dephasing (FSD) was evaluated for detecting peripheral arterial disease in diabetes. Forty-five patients underwent contrast enhanced MRA (CE-MRA) and NCE-MRA in calf and foot on a 1.5T MR system. Image quality and significant arterial stenosis50%was assessed by two experienced radiologists. The technique demonstrated a comparable percentage of diagnostic arterial segments and image quality with CE-MRA, and a high diagnostic accuracy for detecting significant arterial stenosis. It can be used as an alternative method for the detection of lower-extremity arterial disease in diabetic patients.