Abstract #0979

White Matter Involvement in Mild Cognitive Impairment & Mild Alzheimers Disease Using Whole-Brain Probabilistic Tractography Normalization

Oranan Tritanon¹, Jiraporn Laothamatas¹, Chewarat Wirojtananugoon¹, Witaya Sungkarat¹, Chakrit Sukying², Sirintorn Chansirikarnjana³

¹Advanced Diagnostic Imaging and Image-Guided Minimal Invasive Therapy Center and Radiology Dept., Ramathibodi Hospital Faculty of Medicine, Mahidol University, Rajataewe, Bangkok, Thailand; ²Department of Psychiatry, Ramathibodi Hospital Faculty of Medicine, Mahidol University, Rajataewe, Bangkok, Thailand; ³Department of Medicine, Ramathibodi Hospital Faculty of Medicine, Mahidol University, Rajataewe, Bangkok, Thailand

Voxel-wise group analyses of DTI in AD, MCI, and age-matched control group based on a new whole-brain probabilistic tractography normalization process revealed very statistical significant changes among the groups.