Maureen N. Hood1, 2, Ting Song1, 3, Peter Bedocs4, John F. Capacchione4, Christine E. Kasper2, 5, Mark C. Haigney6, Vincent B. Ho1
1Radiology & Radiological Sciences, Uniformed Services University, Bethesda, MD, United States; 2Graduate School of Nursing, Uniformed Services University, Bethesda, MD, United States; 3Global Applied Science Laboratory, GE Healthcare, Bethesda, MD, United States; 4Anesthesiology, Uniformed Services University, Bethesda, MD, United States; 5Nursing, department of Veteran Affairs, Washington, DC, United States; 6Cardiology, Uniformed Services University, Bethesda, MD, United States
T1 mapping may be a promising technique to quantify myocardial changes in heart failure even when the subject cannot hold their breath. T1 mapping using modified look-locker with saturation recovery in this small swine study shows a quantitative difference in T1 value between healthy baseline and heart failure hearts. The immunochemistry suggests a change in amounts of Type I, III and VI collagen in the myocardium between the control and heart failure swine, but more research needs to be done.