Jian-Jia Chiu1, Yi-Ru Lin1, Shang-Yueh Tsai2, 3
1Department of Electronic Engineering, National Taiwan University of Science and Technology, Taipei, Taiwan; 2Graduate Institute of Applied Physics, National Chengchi University, Taipei, Taiwan; 3Reasearch Center for Mind, Brain and Learning, National Chengchi University, Taipei, Taiwan
Early detection of non-alcoholic fatty liver disease can prevent further complications such as steatohepatitis, fibrosis and cirrhosis. Previous we have shown that proton echo planar spectroscopic imaging (PEPSI) is able to detect spatial distribution of liver fat content. Here we further investigated the influence of T2 relaxation effects. Non-water suppressed liver spectra were obtained using PEPSI sequence. PEPSI scans were repeated 8 times to observe the reproducibility of T2 correction. Our results showed that hepatic fat content distribution with T2 correction can be achieved in less than 3 minutes with our protocol. And the measured fat content is highly reproducible.