Michael W. Harrell1, Katherine L. Wright2, John Jesberger, 13, Luis Landeras1, 3, Dean Nakamoto1, 3, Smitha Thomas1, 3, Dominik Nickel4, Randall Kroeker4, Mark A. Griswold2, 3, Vikas Gulani1, 3
1School of Medicine, Case Western Reserve University, Cleveland, OH, United States; 2Dept. of Biomedical Engineering, Case Western Reserve University, Cleveland, OH, United States; 3Dept. of Radiology, University Hospitals of Cleveland and Case Western Reserve University, Cleveland, OH, United States; 4Siemens Medical Solutions, Erlangen, Germany
CAIPIRINHA (Controlled Aliasing In Parallel Imaging Results IN Higher Acceleration) is an imaging technique that modifies aliasing artifacts during image acquisition, which potentially allows for a more robust parallel imaging reconstruction with fewer aliasing artifacts. Here this was tested by comparing CAIPIRINHA against a clinically standard GRAPPA acquisition for highly accelerated breath hold liver scans. Evaluation of the image quality of CAIPIRINHA by three blinded, untrained radiologists demonstrated a statistically significant improvement in clinical image quality in comparison to a standard GRAPPA.