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Abstract #1476

Dynamic Analysis of Breast Lesions: Can We Use the Wash-In Phase Instead of the Wash-Out Phase?

Ritse M. Mann1, Roel DM Mus1, Christian Geppert2, Cindy PM Frentz1, Nico Karssemeijer1, Henkjan Huisman1, Bram Platel1, 3

1Radiology, Radboud University Nijmegen Medical Centre, Nijmegen, Gld, Netherlands; 2Oncology, Siemens Healthcare, Erlangen, Germany; 3Fraunhofer MEVIS, Bremen, Germany


Initial maximum slope of enhancement as derived from ultrafast TWIST images acquired during contrast inflow provides a strong discriminator between benign and malignant disease that outperforms classic 3-timepoint analysis. By using a fixed grid of relative enhancement versus time curve types can be defined that can be easily implemented in current radiological practice.